International Research journal of Management Science and Technology

  ISSN 2250 - 1959 (online) ISSN 2348 - 9367 (Print) New DOI : 10.32804/IRJMST

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IN SITU AND IN VITRO PHARMACOGNOSTIC STUDY OF CALOTROPIS PROCERA

    2 Author(s):  TANUSHREE DUTTA,DESH DEEPAK

Vol -  8, Issue- 12 ,         Page(s) : 418 - 432  (2017 ) DOI : https://doi.org/10.32804/IRJMST

Abstract

The nature has provided a complete storehouse of remedies to cure ailments of mankind. About 80 per cent of the world's population depends partially or wholly on traditional medicine for its primary health care needs. Herbal medicines as the major remedy in traditional medical system have been used in medical practice for thousands of years and have made a great contribution to maintain human health. The global interest in study and practice of crude drugs has therefore, considerably increased during the last two decades because of growing awareness about the toxicity and side effects of synthetic drugs, their limitations in many areas of therapy, comparatively high cost and often drug beyond the reach of common man. The Pharmacognostic study of Calotropis procera leaves was carried out to detect the adulteration. The plant was analyzed for its preliminary screening of phytochemicals. The results reveal that the plant shows presence of bioactive constituents comprising alkaloids, reducing sugar, anthraquinones, saponins, flavanods and tannins. In the present study medicinal uses, Phytochemical analysis and Pharmacognosy of plant have been revived.

1. Arokiryaraj S, Sripriya N, Bhagya R, Prameela L and Udayaprakash NK (2012). Phytochemical screening, antibacterial and free radical scavenging effects of Artemisia nilagirica, Mimosa pudica and Clerodendrum siphonanthus- An in- vitro study. Asian Pacific Journal of Tropical Biomedicine, pp, 601- 604.
2. Alshukri SAA, Al-Saadi AH and Zaidan HK (2018). Assessment of antihyperglycaemic activity of Calotropis procera leaves extract on Alloxan-Induced diabetes male rats. Journal of Babylon University/Pure and Applied Sciences 26(3): 459-463.
3. Bhagat M, Arora JS adn Saxena AK (2010). In vitro cytotoxicity of extracts and fractions of Calotropis procera (Ait.) roots against human cancer lines. International Journal of Green Pharmacy 41(2): 221-232.
4. Chopra RN, Nayar SL and Chopra IC (1956). Glossary of Indian Medicinal Plants. Council of Scientific and Industrial Research. New Delhi, pp., 46.
5. Deshpande S, Deshpande K and Tomar E (2018). Calotropis gigantean: A phytochemical potential. World Journal of Pharmaceutical Research 7(11): 402-409.
6. Halu B and Vidyasagar GM (2014). Comparative studies on the antibacterial efficacy of crude leaf extracts of Calotropis spp. at Gulbarg Karnataka. World Journal of Pharmacy and Pharmaceutical Sciences 3(2): 2229-2235.
7. Himalaya (2002). Herbal Monograph, Himalaya Herbal Healthcare, www.himalayahealthcare/research/index.hlm.
8. Kawo AH, Abhullahi BA, Sule MS, Hayatu M and Dabai YU (2013). Comparative analysis of th phytochemical, proximate and elemental composition of Calotropis procera 9Ait. F.) Ait. F. Latex and Moringa oleifera (Lam) seed powder. Life Journal of Science 15(3): 555-562.
9. Khan IN, Sarker MMI and Ajrin M (2014). Sedative and anxiolytic effects of ethanolic extract of Calotropis gigantean (Asclepiadaceae) leaves. Asian Pacific Journal of Tropical Biomedicine 4: 400-404.
10. Khanzada SK, Shaikh W, Kazi TG, Sofia S, Kabir A, Usmanghani K and Kandhro AA (2008). Analysis of fatty acid, elemental and total protein of Calotropis procera medicinal plant from Sindh, Pakistan. Pakistan Journal of Botany 40(5): 1913-1921.
11. Kumar G, Karhik L and Rao KVB (2010). Antibacterial activity of aqueous extract of Calotropis gigantean leaves- An in vitro study. International Journal of Pharmaceutical Sciences Review and Research 4(2): 141-146.
12.  Kori P and Alawa P (2014). Antimicrobial activity and phytochemical analysis of Calotropis gigantean root, latex extracts. IOSR Journal of Pharmacy 4(6): 7-11.
13.  Mainasara MM, Aliero BL, Aliero AA and Dahiru SS (2011). Phytochemical and antibacterial properties of Calotropis procera (Ait.) R.Br. (Sodom Apple) Fruit and Bark extracts. Internaitonal Journal of Modern Botany 1(1): 8-11.
14.  Manandhar NP and Manandhar MP (1990). Folklore medicine of Chitwan District, Nepal, Enthnobotany. 2, 33.
15.  Maurya R, Srivastava S, Kulshreshta DK, Gupta CM (2004). Traditional remedies for fertility regulation. Curr. Med. Chem. 11: 1431 – 1450.
16.  Mojab F, Kamalinejad M, Ghaderi N and Vahidipour HR (2003). Phytochemical screening of some species of Iranian Plants. Iran. J. Pharm. Res., 2; 77 – 82.
17.  Moustafa AMY, Ahmed SH, Nabil ZI, Hussein AA and Omran MA (2010). Extraction and phytochemical investigation of Calotropis procera: Effect of plant extracts on the activity of diverse muscles. Pharmaceutical Biology 48(10): 1080-1190.
18.  Nadkarni KM and Nadkarni AK (1976). In: Indian Material Medica, Vol. 1. Bombay Popular Parkashan Pvt. Ltd., pp. 237 – 241.
19.  Patil SM and Saini R (2012). Antimicrobial activity of flower extracts of Calotropis gigantean. International Journal of Pharmaceutical and Phytopharmacological Research 1(4): 142-145.
20.  Saif MMS, Al- Fakih AA and Hassan MA (2017). Antibacterial activity of selected plant (Aqueous and methanolic) extracts against some pathogenic bacteria. Journal of Pharmacognosy and Phytochemistry 6(6): 1929-1935.
21.  Shobowale OO, Ogbulie NJ, Itoandon EE, Oresgun MO and Olatope SOA (2013). Phytochemical and Antimicrobial evaluation of aqueous and organic extracts of Calotropis procera Ait Leaf and Latex. Nigerian Food Journal 31(1): 77-82.
22.  Shukla S and Kapoor K (2018). In vivo and in vitro phytochemical screening, comparative analysis and sub culturing effect of Calotropis procera. Austin Journal of Biotechnology and Bioengineering. Austin Journal of Biotechology and Bioengineering 5(2): 1097-1105.
23.  Verma R, Satsangi GP and Shrivastava JN (2013). Analysis of phytochemical constituents of the ethanolic and chloroform extracts of Calotropis procera using gas chromatography-mass spectroscopy (GC-MS) technique. Journal of Medicinal Plants Research 740): 2986-2991.

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