CONSOLIDATION OF FEAR MEMORY AND ITS’ RECALL ARE CUE DEPENDENT
3
Author(s):
VANDANA RANJAN , M.Y. KHAN , ANAND PRAKASH
Vol - 3, Issue- 1 ,
Page(s) : 201 - 206
(2012 )
DOI : https://doi.org/10.32804/IRJMST
Abstract
Living organism acquire long-lasting memories for threatening events called fear memories. Recall of fear memory in presence or absence of harmful stimuli is dependent of re-exposure to associated cue or context to make the organism able to become alert for coming threat if arise again in future. In present study behavioral outcomes were investigated in response to paired and unpaired CS-US presentation using Pavlovian classical conditioning model. The fear response during fear acquisition (experiencing harmful-fear stimulus) was found independent of paired cue/context presentation while fear response during recall of fear memory was dependent of paired cue or context presentation. Results suggested that fear memory formation require association of harmful stimulus with cue and without cue the animal was unable to reproduce the fear response if threatening stimulus was absent.
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